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Femina ; 43(1)jan.-fev. 2015.
Article in Portuguese | LILACS | ID: lil-754438

ABSTRACT

Este artigo objetivou oferecer uma visão atual do papel dos marcadores gênicos no carcinoma de endométrio. Os principais genes descritos são o TP53, o Bcl-2, o c-erbB2 e o p16. Nos últimos anos, com a ampliação do conhecimento na área de biologia molecular, tem sido sugerido que os marcadores biológicos possam ser tão ou mais importantes do que os fatores prognósticos convencionais.


The main of this study is offer the present situation of genic markers in endometrial carcinoma. The principal genes have been described are TP53, Bcl-2, c-erbB2 and p16. In the last few years, thanks to improvements in molecular biology, some biological markers have been suggested to be as important as or more important than conventional prognostic factors.


Subject(s)
Humans , Female , Adult , Endometrial Neoplasms , Biomarkers/analysis , /physiology , /physiology , Hysterectomy , Genetic Markers/genetics
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